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Supportive Treatment For Azoospermia

New Supportive Treatment for Azoospermia

Men who are found to have primary testicular failure usually can not be fully cure and will likely require the use of surgical sperm retrieval methods to recover viable sperm for IVF.
We highly recommend taking the six months course of SpermHope® treatment for two reasons:


First, our treatment can improve your sperm count in the semen and avoid the biopsy (in rare cases sperm count can be normal).


Second, if the semen does not contain any sperm, this treatment improves your success chances of testicular sperm extraction.


Everyone should consider testicular sperm extraction after this treatment.

 

SpermHope® Idea

Many cases of prolonged azoospermia are a result of killing all the spermatogonial stem cells inside the testis by infection or other reasons that we do not know. In other instances, however, the stem spermatogonia survive but fail to differentiate into sperm.

Our examination of the hormonal status of azoospermic cases revealed that the failure of the differentiation of spermatogonia could not be the result of insufficient stimulation by gonadotropins or testosterone. Follicle-stimulating hormone (FSH) levels were 1.5-fold normal and luteinizing hormone (LH) and testosterone levels remained unchanged.


Researchers have hypothesized that in azoospermia cases, testosterone might actually be inhibiting the spermatogonial differentiation. Many scientists have conducted numerous studies based on this hypothesis and researchers have suppressed testosterone by treating azoospermic rats with gonadotropin releasing hormone (GnRH) antagonists that prevented the blockage of spermatogonial differentiation. Although the spermatogonia differentiated, they could not progress past the round spermatid stage as long as the testosterone was suppressed.


We expected the testosterone to support normal spermatogenesis, but it appeared to inhibit this process in azoospermia conditions.

 

Therefore, we performed more studies to confirm that testosterone is inhibitory in azoospermia cases. We noted that testosterone action in normal spermatogenesis supports spermatocyte and spermatid development has only small quantitative effects on spermatogonia. So testosterone’s newly discovered inhibitory phenomenon is an extra action and does not replace its usual action.

 

 

 

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SpermHope Kit Cost 199$ for Six Months Treatment

 

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To understand the SpermHope® Idea we recommend you watch or read about:

AzoospermiaSpermHope® ideaSpermHope® Reasearch